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Dileep Vijayan

I am Dileep Vijayan, native of Kerala (the god’s own country), India. I am an active researcher in the area of computational and structural biology. I am interested to work on multi-disciplinary research projects which includes both computational and experimental studies. 

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My primary research focus is performing chemical biology research to propose lead molecules majorly for the drug targets in neurodegenerative disorders, epigenetics, cancer and inflammatory-related diseases by combining multiscale computational approaches with x-ray crystallography and other biophysical methods. 

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I am keen to exploit my expertise in computational and structural biology to study the structure, function and dynamics of various biological macromolecules and efficiently customize them for various purposes ranging from drug discovery to nanotechnology. In addition to that, I am also interested to study the structure, dynamics and catalysis of the various chemical systems by means of classical molecular dynamics simulations coupled with QM/MM simulations and free energy estimation. Learning about the 'mechanistic biology of pathogenic mutations' and 'role of hydration on the plasticity and function of the protein' are some of the other interests.   

 

My passion is to become an independent researcher in the area of computational and structural biology and to perform high quality research for the betterment of humankind.

Educations  

 

  • Ph.D : “Studies on interactions of selected indole derivatives with their target proteins associated with alzheimers disease and neuroinflammation”. Dept. of Biotechnology and Microbiology, Kannur University, India. 2015.

 

  • Master of Science in Bioinformatics : KSR college of Arts and Science,  Thiruchengode, Tamil Nadu, India. 2005.

 

  • Bachelor in Chemistry : St. Thomas College, Thrissur, Kerala, India. 2003.

 

Skills 

 

  • Computer aided lead design and protein engineering.

 

  •  X-ray crystallography and structural analysis of biological macro-molecules.

 

  • Performing multi scale computational approaches like molecular dynamics, free energy perturbations, high throughput virtual screening.

 

  • Expression, purification and biophysical characterization of proteins and their interactions with ligands.

 

  • In vitro cell culture and cytotoxicity studies.

 

  • Other basic computational skills.

 

Professional experiences 

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  • Scientist-D : 09.06.2021 to present                                                                                                                                                   Laboratory Jubilee Centre for Medical Research, Thrissur, Kerala, India.                                                                                                                              

  • Visiting Scientist : 01.06.2021 to present                                                                                                                                                   Laboratory for Structural Bioinformatics, RIEKN, Yokohama, Japan.                                                                                                                               

  • Research Scientist : 01.12.2018 to 31.05.2021                                                                                                                                                  Laboratory for Structural Bioinformatics, RIEKN, Yokohama, Japan.

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  • Visiting Researcher (JSPS Postdoctoral Fellowship) : 30.11.2016 to 29.11.208.                                                                                 Laboratory for Structural Bioinformatics, RIEKN, Yokohama, Japan.

 

  • International postdoctoral Fellow (Takeda Science Foundation) : 09.05.2016 to 15.11.2016.                                                   

       Laboratory for Structural Bioinformatics, RIEKN, Yokohama, Japan.

 

  • Institute Postdoc Fellow : 22.12.2014 to 26.04.2016.                                                                                                                                School of Chemistry, IISER - Thiruvananthapuram, Kerala, India.

 

  • Junior Scientist : 01.07.2014 to 20.12.2014.                                                                                                                                                    Dept. of Computational Biology and Bioinformatics, University of Kerala, India

 

  •  Research Fellow : 18.11.2008 to 27.06.2014.                                                                                           

        Dept. of Biotechnology and Microbiology, Kannur University, Kerala, India. ​​​

 

  • Research Assistant : 19.04.2008 to 30.09.2010.                                                                                                                                        Bioinformatics Infrastructure Facility, Dept. of Biotechnology and Microbiology, Kannur University, India.

 

  • Research Associate : 11.10.2007 to 18.04.2008.                                                                                                                                          Bioinformatics Centre (DIC), Kerala Agricultural University, Kerala, India.

 

  • Senior Research Fellow : 01.03.2007 to 10.10.2007.                                                                                                                                    Bioinformatics Centre (DIC), Kerala Agricultural University, Kerala, India.

 

  • Technical Assistant : 26.06.2006 to 28.02.2007.                                                                                                            

        Kerala Forest Research Institute, Kerala, India.

 

  • Research Fellow : 06.02.2006 to 24.06.2006.                                                                                                                                                   Kerala Forest Research Institute, Kerala, India.

 

  • Project Assistant : June 2005 to February 2006.                                                                                                                                            Kerala Forest Research Institute, Kerala, India.

                   

       To Request my CV

      

 

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